Hibiscus sabdariffa L. is widely used in the preparation of beverages. Active component of this plant exhibit antimicrobial activity, yet little research has been conducted on their possible use in food systems as antimicrobials. The use of this tradicinal medicinal plant as natural antimicrobial agents is gaining popularity. The Hibiscus sabdariffa is widely used for the treatment of diseases. The present study is the continuation of a program aimed at investigation of antimicrobial properties of Hibiscus sabdariffa leaf extract. The antibacterial activity was evaluated according to the disk diffusion method by using Gram positive; B. subtilis, S. aureus and Enterococcus and Gram negative; E. coli, Acetobacter, citrobacter, bacteria. This study shows that methenolic leaves extracts of Hibiscus sabdariffa Linn inhibit the growth of microorganism’s dose dependently. The appear results confirm that the antibacterial activity of Hibiscus sabdariffa leaves.

Sansevieria roxburghiana is the most popular ornamental plant with long rhizomes and fibrous roots possessing traditional healing properties. In the present study, ethyl acetate extracts from Sansevieria roxburghiana leaves were subjected to GC-MS analysis to study the important phytochemical constituents responsible for the various pharmacological activities. The crude extracts of ethyl acetate were obtained by soxhlet method. The GC-MS analysis of ethyl acetate extract from Sansevieria roxburghiana revealed the presence of fifteen phytochemical constituents in the leaves part. Out of 15 phytochemical compound, 13 phytochemical compounds are bio-active compounds were identified by GC-MS. The phytochemical constituents were identified by comparing their retention time and peak area with that of literature and by interpretation of mass spectra. Nine major phytochemical constituents were present in leaves parts are 1,4-Benzenedicarboxylic acid, 2, 5-dimercapto (9.6%), N, 3-Diphenyl-1, 2-carbazoledicarboximide (12.6 %), 3-(3, 5-Dimethylphenylamino)-1, 7, 7-trimethylbicyclo [2.2.1] heptan-2-ol (9.4%), Estra-1, 3, 5(10)-triene-17-one, 3, 4-bis[(trimethylsilyl)oxy]- (12.7%), Isoxazole, 5-[3, 3-dicyano-1-cyclohexylidine-2-morpholino-prop-2enyl)]-3-p-methoxyphenyl- (12.7%), 9, 9-Diazidofluorene (8.9%), Condyfolan, 14, 19-didehydro-1-methyl- (14E)- (6.6%), 5, 6-Dicarbadecarborane(12), 5, 6-dimethyl-(7.3%), and Cholestan-26-oic acid, 3, 7, 12-trihydroxy-,(3a', 5a', 7a', 12a')- (11.6%).

Papaya is often proverbial for its food and nutritionary values throughout the globe. The properties of papaya fruit and other parts of the plant are also well known in traditional system of medicine. During the previous few decades tidy progress has been achieved concerning the biological activity and healthful application of papaya and currently it's thought-about as valuable nutraceutical fruit plant. Carica papaya is employed in ayurvedic medicines from terribly very long time. It is used as medication, antioxidant, diuretic, antibacterial, abortifacient, vermifuge, hypoglycemic, antifungal activity, antihelmenthic and immunomodulatory etc. Scientific evidences counsel their versatile biological perform that supports its ancient use in numerous diseases. Phytochemical studies shows that plant fruit tree contains in the main alkaloids carpaine, pseudocarpaine, tannins, flavnoids, carcin, gamma terpine, organic compound carposides, sugars etc. The plant has effective pharmacological activity such as anti-inflammatory, antioxidant, diuretic, antibacterial, abortifacient, hypoglycemic, antifungal, antihelmenthic and immunomodulatory, hepatoprotective and anticonvulsant activity.

The study on the larvicidal potential of different solvent crude (chloroform, water, acetone, hexane, ethanol, methanol) leaf extract of Vetiveria zizanioides against the dengue vector. The Aedes aegypti showed the root ethanolic extracts of vetiver contains alkaloids, flavanoides, saponins, tannins and steroids. The compounds are known to possess insecticidal and larvicidal activities. The chloroform extract shows the most effective larvicide among the various solvent extracts with the percentage mortality of 95% and 70% in 48 and 24hrs of exposure respectively. The high larvicidal activity is supported by the presence of phytochemicals such as alkkloides, saponins, tannins, flavanoides and steroids which showed combination effects interms of larvicidal action to mosquito larvae. The ethanolic extract of vetiver also shows good larvicidal activity 88% in 48hrs 68.42% in 24hrs. The water extract of vetiver shows no responds to mosquito larvae. The hexane extract and acetone extract having less effective against mosquito larvae. The LC - Mass spectra obtained determines the active fraction of chloroform had a major peak at retention time of 14.76 - 14.2 min with 621.31 peak area. These vetier extracts possessed different range of larvicidal property which may be used as a traditional mosquito control agent.

Parkinson’s disease is a progressive neurodegenerative disorder characterised by the selective loss of dopaminergic neuron of substantia nigra pars compacta. Haloperidol (intraperitoneally in the dose of 2mg/kg) is commonly used to induce Parkinson‟s disease in rat. It blocks dopamine receptors present in the straitum, thus induces Parkinson‟s disease. Valsarten (ARBs) are widely used compounds therapeutically effective in cardiovascular disorders, renal disease, the metabolic syndrome, and diabetes. It has been more recently recognized that are neuroprotective and have potential therapeutic use in many brain disorders. Aim of this study to compare Valsarten with standard drug in vivo neuroprotective in haloperidol induced animal model in Parkinson’s disease. Animals treated with Valsarten (Group IV) showed a nonsignificant difference in the 0th day (185.35) and then a gradually increase in locomotor activity on the 4th and 7th day respectively (165.23 ± 21.8 and 178.58), on the 14th day it further increase to (198.34). The increased motor rigidity was same in all the groups on 7th day one day after stopping the Parkinson inducing drug haloperidol. No significant difference was observed between the treated and untreated groups on 7th day. On 14th day much more recovery of muscle tone was noted in all the groups evidenced by rota rod. But complete recovery was not observed in all the experimental groups 7 days after stopping the standard and investigational drugs. Valsarten treated group (Group IV), a significant decrease in catalepsy was seen on 4th and 7th day as compared to the Haloperidol treated group (Group II) and increase on 14th day of the treatment. Whereas no significant difference in catalepsy was seen when Group VI compared to standard treated group (Group III). It confirmed the neuroprotective effect Valsartan in Haloperidol induced Parkinson’s Disease.