Therapy of root canal may be carried out as an alternative to dental extraction on a tooth in which the nerve has been injured or has died. Management of root canal is carried out because the offending canal is infected or the pulp severely inflamed. The aim of canalis radicis dentale treatment is to eliminate bacteria from, and prevent their further entry to the root canal system. The method involves cleaning and removal of any remaining bacteria and nerve canal contents. Removal of any infection improves the chance of success, and irrigation of the canal with certain types of solutions during the procedure can be helpful in achieving this. Several antimicrobial irrigating solutions are available. Hypochlorite solution; e.g. NaOCl in a variety of strengths has been used by dentists for many years, but concerns have been raised about its toxicity and the occasional report of pain when higher concentrations are used. An antimicrobial; e.g. chlorhexidine has also been used in a variety of concentrations as either a solution or gel. Antibiotic and a detergent (MTAD) combination have been recently developed and are being used increasingly. Shaping the canal with hand and rotary instruments under constant irrigation to remove the inflamed and necrotic tissue, microbes/biofilms, and other debris from the root-canal space. The purpose of using instrumentation is to facilitate effective irrigation, disinfection, and filling.

The aim of present study was to screen the phytoconstituents and to investigate in vitro antioxidant potential of ethanolic leaf extract of the plant Aquilaria malaccensis (Thymelaeaceae). The antioxidant activity was assessed by invitro methods using DPPH assay, Hydroxyl radical Scavenging assay, Superoxide radical scavenging assay method. And the plant extract shows significant antioxidant property. Preliminary phytochemical investigations were also performed on the leaves of Aquilaria malaccensis which shows the presence of saponins, alkaloids, flavonoids, terpenoids, tannins, carbohydrate, glycosides, coumarin, emodins, anthraquinones, resins, phenols.

Spirulina, a Blue-Green Alga (BGA) that are the most primitive life forms on earth and have been consumed as food or medicine by humans for centuries. Spirulina contain various bioactive components, such as phycocyanin, carotenoids, essential amino acids, γ-linolenic acid, fibers, and plant like sterols, B vitamins, calcium, phosphorous, iron, pigments such as β-carotene, xanthophylls, and chlorophyll, and other bioactive compounds which can promote optimal health in humans. Studies have demonstrated that Spirulina species or their active components have plasma total cholesterol and triglyceride-lowering properties due to their modulation of intestinal cholesterol absorption and hepatic lipogenic gene expression. Furthermore, Spirulina is known to inhibit lipid peroxidation and have free radical scavenging activity, which can be beneficial for the protection against oxidative stress. The aforementioned effects of Spirulina can contribute to the prevention of many metabolic and inflammatory diseases. This review provides an overview of the current knowledge of the health-promoting functions of Spirulina against major diseases and health threats that prevail today and the protective effects of Spirulina against these diseases.

Azadirachta indica is known for its use in the traditional treatment of malaria, leprosy, cancer, intestinal helminthiasis, respiratory disorders, inflammation, constipation, blood morbidity, diabetes, rheumatism, biliary infections, dermatological complications, itching, ulcers and more. Azadiradione (AZD), as a major constituent in the seed of A. indica, was found to have many different biological activities related to the traditional uses of A. indica. It was found effective against inflammation peptic ulcer, Huntington’s disease, mycobacteria, diabetes, cancer, malaria along with other activities as bone cells differentiation and mineralization, anti-nociceptive, anti-fungal, cytotoxic and insect anti-feedants activities. Azadiradione may present a potential multi-targets with new therapeutic approach.

Present study was designed to evaluate the antibacterial activity of Abutilon indicum (Stem bark) methanol extract. Antibacterial activity was tested against Gram-positive bacteria i.e. Staphylococcus aureus and Gram negative bacteria Escherichia coli. Evaluations were based on the zone inhibition by using cup plate method. Results showed that Abutilon indicum showed highly significant results against both the bacteria.