The primary function of nutrition is to provide adequate nutrients to fulfill the requirements of a healthy diet, while giving the customer a sense of satisfaction and well-being. The hypothesis that diet also controls and modulates various body functions and thus contributes to the state of good health needed to reduce the risk of some diseases is supported by the most recent knowledge in bioscience. Synbiotics have potential functional effects on mineral bioavailability, but also, more systemically speaking, on lipid metabolism. Potential health benefits may concern reduction of the risk of intestinal infectious and coronary diseases.
N. Keerthi, P. Jayasree*, J. Praveen, M. Sreeja, J. Yeshashwini, J. V. C. Sharma.
Abutilon indicum Linn (Malvaceae) is a shrub distributed throughout India. The various parts of the plant (leaves, roots, seeds and seed oil) are widely employed by various tribal communities and forest dwellers for the treatment of sort of ailments. The plant contains mucilage, tannins, β-sitosterol, asparagines, flavonoids, alkaloids, hexoses, nalkane mixtures, alkanol, gallic acid and sesquiterpenes as major phytoconstituents. Abutilon indicum has several activity reported as anti-inflammatory, antiproliferative, anti-arthritic, analgesic, sedative, antioxidant, antimicrobial, hepatoprotective, antidiabetic, anticancer, anti-diarrhoeal, anticonvulsant, larvicidal, wound healing, antiasthmatic, diuretic, immunomodulatory and anti-estrogenic activity. The methanolic extract of Abutilon Indicum stem bark also showed significant antifungal activity by showing zone of inhibition of 19.23 ± 0.11and 13.33 ± 0.16 on nutrient agar medium plate against Candida albicans and Aspergillus niger when compared zone of inhibition of 25.55 ± 0.23 and 27.32 ± 0.29 of standard ketaconazole at 30µg/disc. The results were noted for zone of inhibition. The extract (methanolic) possesses zone of inhibition is proportional to its antimicrobial activity of standard antibiotic. The methanolic extract of Abutilon Indicum stem bark also showed significant antifungal activity by showing significant inhibition against Candida albicans.
Medicinal plants are gift of God, to cure infinite number of diseases in human beings and other living organism. These Plant materials have been extensively used in the indigenous system of medicine which is mention in the Ayurveda and other Indian literature. In this present experiment we had studied about to evaluate in-vitro anthelmintic activity of Clitoria ternatea by using leaves extract. Anthelmintic activity was tested against Indian earthworm Pheretima posthuma. Extraction of Clitoria ternatea demonstrated potent anthelmintic activity tested against Indian earthworm Pheretima posthuma. The dose-dependent anthelmintic efficacy of the fractions was quite similar to that of piperazine citrate The result obtained in the study led to the conclude that leaves of the mangrove plant, high level of polyphenolics and show significant anthelmintic activity. Clitoria ternatea Linn known as Tulsi in India is a sacred plant for Hindus known from centuries and being used in Ayurveda for its varied healing properties belonging to the Fabaceae (Pipilionaceae) family. To this purpose we have studied in vitro antihelminthic activity of C. ternatea in comparison with albendazole.
As a PPAR gamma agonist, pioglitazone is used to treat type 2 diabetes mellitus. It has been associated with a decrease in bone mass and a higher risk of fracture in those with type 2 diabetes. The goal of this study was to look into the effect of geraniin in preventing pioglitazone-induced bone loss. For diabetes induction, streptozotocin was used. For eight weeks, diabetic rats were given pioglitazone (300mg/kg) and geraniin (40mg/kg) alone or in combination. At the end of the experiment, BMD of the femur and lumbar vertebrae was measured by dual-energy X-ray absorptiometry (DXA). Glycoslyted haemoglobin serum and serum glucose were also examined. Pioglitazone and geraniin, both alone and in combination, dramatically lowered high blood glucose levels. When compared to the positive control, pioglitazone treatment dramatically reduced HBA1C levels. The combination of geraniin and pioglitazone reduced blood glucose and HBA1C levels considerably. Pioglitazone had negative effects on BMD in the femur and lumbar vertebrae, while geraniin therapy significantly improved these effects. This study suggests that geraniin supplementation in diabetic individuals using pioglitazone could be an appropriate method for reducing pioglitazone-induced bone loss.
In albino rats, the effect of an alcoholic extract of Buchananialanzan (Buchanania lanzan) alone and in combination on wound healing was investigated. In this study, incision and excision wounds were used as wound models. Breaking strength was measured in incision wounds, whereas epithelialization and wound contraction were measured in excision wounds. A substantial (P<0.001) difference was found in the dexamethasone-treated group. In the incision wound model, the extract of Buchanania lanzan a lone and its combination considerably increased wound breaking strength when compared to control (P<0.001). In comparison to control wounds, the combination treated wounds showed signifiantly increased (P<0.001) faster epithelialization and wound contraction rate. The use of Buchanania lanzan +β-glucans in the topical therapy of wound healing are supported by increased wound contraction and tensile strength.
Krishnaraju Venkatesan*, Rajalakshimi Vasudevan, Absar Ahmed Qureshi, Ester Mary Pappiya, Premalatha Paulsamy, Rama Ramaiah, Kalpana Krishnaraju.