Objective: The current study was undertaken to quantify the presence of phytochemicals constituents and to examine antimicrobial analysis of the different dried parts of G. polycaulon in two different solvents. Methods: G.polycaulon plants were collected from The Nilgiris District, South India and coarsely powdered for organic solvent extraction with aqueous, and ethanol solvents. Then all the extracts obtained were subjected for phytochemical screening and antimicrobial study with standard procedure. Results: The presence of major phytochemicals quantitatively in all solvent extracts. The aqueous leaf extract of G. polycaulon recorded significant antibacterial and antifungal activity against all the test bacteria and fungi than ethanolic extracts. Conclusion: The present study strongly supports that the crude solvent plant extracts contain medicinally important bioactive compounds due to the strongly presence of secondary metabolites which can be used to fight against resistant organisms for the treatment of different diseases.
K. Shanmugapriya*, T. Senthil Murugan, Thayumanavan Tha.
The present study was aimed to investigate the anti-hyperlipidaemia activity of Commniphora mukul bark and seeds powder on high fat high cholesterol (HFHC) fed rats group. The effect of Commniphora mukul bark and seeds powder on serum and tissue lipid profile of albino rats were studied. In addition, body weight changes, organs weight, relative liver size and food consumption were evaluated in the entire existence groups. Results revealed that in both studies Commniphora mukul bark and seeds powder showed the reduction in serum and tissue phospholipid, free fatty acid, triglycerides and total cholesterol levels and increases the protein and albumin level in experimental groups as compare to HFHC group. The value of phospholipid, free fatty acid, triglycerides and total cholesterol where increased in HFHC groups whereas the levels decreased by the treatment with bark and seeds powder with simultaneous increase in protein, albumin and serum HDL levels. Hence the results justify that Commniphora mukul possess anti-hyperlipidaemia activity.
The aim of the study is to carry out the in vivo anti‐inflammatory activity on leaves of Simarouba glauca. The in-vitro anti- arthritic activity of the ethanolic extract Simarouba glauca has been done by on bovine serum protein denaturation method and results are compared with standard. The results are at different concentration (10 to 1000µg/ml). Simarouba glauca showed significant activity at various concentrations. Significant activity was seen at the concentration 73.84% at 1000μg/ml when compared with the standard drug diclofenac sodium.
Jibi Antony*, D. Gnanasekaran, Anupriya Thomas, G. M. Kavana.
This study was performed to investigate the anxiolytic effects of aqueous extract of Matricaria chamomile L (AEMC) in mice using the elevated plus-maze model (EPM) and light dark model. The extract was administered orally in two different doses of 200mg/kg and 400mg/kg were able to increase the time spent and the number of arm entries in the open and closed arms of the elevated plus-maze, also increases the time spent by mice in the illuminated side of the light-dark test, dose of 200mg/kg and 400mg/kg showed more significant increase in comparison with control animals. This effect was comparable to that of the diazepam (5mg/kg p.o.). These results indicate that AEMC is an effective anxiolytic agent.
G. Kiran*, K. Yaminisai, B. Naresh, M. Anand Babu, A. Samba Siva Rao, CH. Ashok Kumar.
Desmodium triflorum is a plant belongs to the family Fabaceae. It is a global species native to tropical regions and introduced to subtropical regions including the southern United States. The plant is having antipyretic, antiseptic, expectorant properties. A decoction is commonly used to treat diarrhoea and dysentery; quench thirst; and as mouthwash. The crushed plant, or a poultice of the leaves, is applied externally on wounds, ulcers, and for skin problems. In general the whole plant is used medicinally for inducing sweat and promoting digestion, anti-oxidant, anti-inflammatory, anti-convulsant and anti-bacterial actions. This review explains the different pharmacological activities of Desmodium triflorum.
Anu K Thankachan*, Meena Chandran, K. Krishnakumar.