Quercetin is polyphenol flavonoid and shows anti-inflammatory, anti-hepatotoxic antihepatotoxic, antiulcer, antiallergic, antidiabetic, antiviral and antioxidant activity. Quercetin is present in herbal plants such as in Annona squamosa. The present research work is to develop a simple, accurate, precise and economic UV spectroscopic method for the estimation of quercetin in Annona squamosal leaves. The estimation of quercetin by spectroscophy is with maximum absorption at λmax 256nm using solvent ethanol. Beer-Lambert’s law is obeyed in the concentration range of 10-50μg/ml and the regression equation y = 0.012x with a regression coefficient (r2) = 0.998 (n=5). For Quercetin, the value of molar absorptivity and Sandell’s sensitivity are 3385.04L/mol/cm and 0.0833μg/cm2. The percentage recovery of quercetin was found to be 69.75%. The % RSD for quercetin showed ±0.22. The method is simple and economic. The developed method was effectively applied for the quantification of Quercetin in food nutrients and herbal plants.

The aim of the present study was to evaluate the antimicrobial, anti oxidant activity of Coriandrum sativum seeds extract plant belongs to family Apiaceae. Antimicrobial activity of alcoholic extracts of these plant leaves were tested against Gram positive and Gram negative bacterial strains by observing the zone of inhibition. Antimicrobial activity was done by disc diffusion method at a concentration of 500µg disc of the extract, using ofloxacin 5μg disc as the standard. The bacterial strains used in the study were Staphycococcus aureus, Bacillus subtilis, Escherichia coli, Proteus vulgaris, the anti oxidant activity of extract was tested by using DPPH radical scavenging method at concentration of 5, 10, 15, 20, 25, 30μgml, using Ascorbic acid as standard. The outcomes of the present study indicated that the alcoholic extract of the Coriandrum sativum seeds shows the significance anti microbial and anti oxidant activity in a concentration of 500µml and 30µgml respectively.

Ficus carica L. is one of the first plants grown by humans, because of their consumption as much as a dry and fresh fruit. It is used in our traditional medicine for the healing of various diseases. Since antiquity, phenolic compounds produced by plants were known as free radical scavengers and as powerful antioxidants. Huge interest has been made by researchers to the traditional uses of medicinal plants against illnesses related to oxidative stress. F. carica L. has three figs yields, early fig stays on the tree; late fig of autumn or figs flowers carries from August to winter and is locally known as Bakor and the green or winter figs. This study aims at performing a preliminary phytochemical analysis to evaluate the phytochemical composition and antioxidant activity of Ficus carica fruit extract. Preliminary phytochemical analysis of Ficus carica extract was done. Ficus carica extract was found to contain phytochemicals like flavonoids, glycoside, protein, terpenoids, saponin, alkaloids, tannins. Antioxidants potential was also estimated by Fenton reaction method. Figs are a good source of many enriching vitamins, antioxidants, and minerals. Improving overall health, balances skin nutrition and helps improve circulation. Further research is required to know the extract mechanism of action of fig as an antioxidant.

Naproxen and albumin microspheres were prepared by using water-in-oil emulsion technology.  The in vitro release profile of targeted delivery system was studied by means of converting numerous processing and method parameters to offer a controlled launch of drug from the microspheres. Targeted drug delivery system was chosen to increase the concentration of delivered drug to the targeted body part of interest only (organs/tissues/ cells) which in turn improves efficacy of treatment by reducing side effects of drug administration. The inherent benefit of this method leads to administration of required drug with its reduced dose and decreased its side impact. The aim of targeted drug delivery is to prolong, localize, target and have a protected drug interaction with the diseased tissue. Quantum of drug at targeted drug delivery site was determined by taking samples at special site via UV spectrophotometer method.

Pharmacogenomics, the use of genomic techniques in the study of pharmacological function, drug disposition and drug action, will allow a better understanding of drug response on an individual level. This is the main basis for a move towards a more individualized medicine, which is commonly referred to as personalized medicine. The long-term future of pharmacogenomics-based drug development looks something like Lead compounds coming out of preclinical pharmacogenomics testing will ideally be chosen based on the fact that they are metabolised and eliminated by several alternative pathways. The Present Review is based on overall concept of pharmacogenomics and its importance in today’s scenario.